COVER STORYS
Publications 2012

Horner A, Goetz F, Tampe R, Klussmann E, Pohl P.
Mechanism for targeting the A-kinase anchoring protein AKAP18δ to the membrane.
J Biol Chem. 2012 Dec 14;287(51):42495-501.

Rossier O, Octeau V, Sibarita JB, Leduc C, Tessier B, Nair D, Gatterdam V, Destaing O, Albigès-Rizo C, Tampé R, Cognet L, Choquet D, Lounis B, Giannone G
Integrins β(1) and β(3) exhibit distinct dynamic nanoscale organizations inside focal adhesions.
Nat Cell Biol. 2012 Sep 30;14(10):1057-67.

Hartmann J, Tran TV, Kaudeer J, Oberle K, Herrmann J, Quagliano I, Abel T, Cohnen A, Gatterdam V, Jacobs A, Wollscheid B, Tampé R, Watzl C, Diefenbach A, Koch J.
The stalk domain and the glycosylation status of the activating natural killer cell receptor NKp30 are important for ligand binding.
J Biol Chem. 2012 Sep 7;287(37):31527-39.

Hulpke S, Baldauf C, Tampé R.
Molecular architecture of the MHC I peptide-loading complex – one tapasin molecule is essential and sufficient for antigen processing.
FASEB J. 2012 Dec;26(12):5071-80

Hinz A, Tampé R.
ABC transporters and immunity: mechanism of self-defense.
Biochemistry. 2012 Jun 26;51(25):4981-9.

Demirel O, Jan I, Wolters D, Blanz J, Saftig P, Tampé R, Abele R.
The lysosomal polypeptide transporter TAPL is stabilized by the interaction with LAMP-1 and LAMP-2.
J Cell Sci. 2012 Sep 15;125(Pt 18):4230-40.

Hulpke S, Tomioka M, Kremmer E, Ueda K, Abele R, Tampé R.
Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex.
Cell Mol Life Sci. 2012 Oct;69(19):3317-27. Epub 2012 May 27.

Wu S, Avila-Sakar A, Kim J, Booth DS, Greenberg CH, Rossi A, Liao M, Li X, Alian A, Griner SL, Juge N, Yu Y, Mergel CM, Chaparro-Riggers J, Strop P, Tampé R, Edwards RH, Stroud RM, Craik CS, Cheng Y.
Fabs enable single particle cryoEM studies of small proteins.
Structure. 2012 Apr 4;20(4):582-92.

Wei R, Gatterdam V, Wieneke R, Tampé R, Rant U.
Stochastic sensing of proteins with receptor-modified solid-state nanopores.

Nat Nanotechnol. 2012 Mar 11;7(4):257-63.

Gu LQ, Ritzo B, Wang Y.
Biosensing: When less is more in a nanopore.
Nat Nanotechnol. 2012 Apr 5;7(4):212-3.

Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R.
Caged glutathione - triggering protein interaction by light.
Angew Chem Int Ed Engl. 2012 Apr 16;51(16): 3960-3.

Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R.
Photoaktivierbares Glutathion - lichtgesteuerte Proteinwechselwirkung.
Angew Chem 2012 Apr 16;124(16): 4027–30.

Publications 2011

Wycisk AI, Lin J, Loch S, Hobohm K, Funke J, Wieneke R, Koch J, Skach WR, Mayerhofer PU, Tampé R.
Epstein-Barr viral BNLF2a hijacks the tail-anchored protein insertion machinery to block antigen processing by the TAP complex.
J Biol Chem. 2011 286: 41402–41412.

Abele R, Tampé R.
The TAP translocation machinery in adaptive immunity and viral escape mechanisms.
Essays Biochem. 2011 Sep 7;50(1):249-64

Roizard S, Danelon C, Hassaine G, Piguet J, Schulze K, Hovius R, Tampé R, Vogel H.
Activation of G-Protein-Coupled Receptors in Cell-Derived Plasma Membranes Supported on Porous Beads.
J Am Chem Soc. 2011 Oct 26;133(42):16868-74. Epub 2011 Sep 29.

Grunwald C, Schulze K, Giannone G, Cognet L, Lounis B, Choquet D, Tampé R.
Quantum yield optimized fluorophores for site-specific labeling and super-resolution imaging.
J. Am. Chem. Soc., 2011, 133 (21), pp 8090–8093

Scholz C, Parcej D, Ejsing CS, Robenek H, Urbatsch IL, Tampe R.
Specific Lipids Modulate the Transporter Associated with Antigen Processing (TAP).
J Biol Chem. 2011 286:13346-13356.

Barthelme D, Dinkelaker S, Albers SV, Londei P, Ermler U, Tampé R.
Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1.
PNAS 2011  108 (8) 3228-3233

Schnell Ramos M, Abele R, Nagy R, Suter Grotemeyer M, Tampé R, Rentsch D, Martinoia E.
Characterization of a transport activity for long-chain peptides in barley mesophyll vacuoles.
J Exp Bot. 2011 Apr;62(7):2403-10. Epub 2011 Jan 31.

Tampé R, Schleiff E.
Highlight: Membrane transport in light of structure, function, and evolution.
Biol Chem. 2011 Jan;392(1-2):3

Bangert I, Tumulka F, Abele R.
The lysosomal polypeptide transporter TAPL: more than a housekeeping factor?
Biol Chem. 2011 Jan;392(1-2):61-6.

Herget M, Baldauf C, Schölz C, Parcej D, Wiesmüller KH, Tampé R, Abele R, Bordignon E.
Conformation of peptides bound to the transporter associated with antigen processing (TAP).
PNAS 2011 108 (4) 1349-1354

Zutz A, Hoffmann J, Hellmich UA, Glaubitz C, Ludwig B, Brutschy B, Tampe R.
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus.
J. Biol. Chem. 2011 286: 7104-7115.