***new address***

Prof. Robert Ernst  

Professor for Molecular Biology

University of Saarland
School of Medicine

Institute of Biochemistry
Kirrberger Strasse
Building 61.4
66421 Homburg (Saar)
Germany

AK Ernst
robert.ernst(at)uks.eu
++49 6841 16 47875

 

 

KING NEWS ***BREAKING

19.5.2017: Harry wins poster price at the 13th Yeast Lipid Conference in Paris. The conference lipid scientists from around the globe. Harry is a fellow of the Austrian Science Fund FWF and is working on the specificity of protein-lipid and protein-membrane interactions. Great stuff, Harry!

10.5.2017: Check out our new lab in Homburg. A photo of our new lab space can be seen in the Campus journal by the University of Saarland here.

15.4.2017: Robert is featured by the Journal of Cell Science as 'Cell Scientists to Watch'. Read about his motivation, path, and hobbies in the current issue of the journal here

1.4.2017: Our proposal "Design principles of living membranes" for the funding scheme "Life?" by the VW foundation has been rewarded with a research grant! It is a joint project with our dear friends Ilya Levental (UTH Houston, Texas, USA), James Sáenz (TU Dresden, GER) and Maya Schuldiner (Weizmann Institute, Tel Aviv, ISR). Fantastico! Go team, go!

***BREAKING NEWS ***
Selected Publications

Ballweg S, Ernst R
Control of membrane fluidity: The OLE pathway in focus
Biological Chemistry (2017) 398, 215-228.

Ernst R*, Ejsing CS*, Antonny B *corresponding authors
Homeoviscous adaptation and the regulation of membrane lipids
Journal of Molecular Biology (2016) 428, 4776-4791.

Covino R*, Ballweg S*, Stordeur C*, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R. *equal contribution
A eukaryotic sensor for membrane lipid saturation.
Molecular Cell (2016) 63, 49-59.

Puth K, Hofbauer HF, Sáenz JP, Ernst R.
Homeostatic control of biological membranes by dedicated lipid and membrane sensors.
Biological Chemistry (2015) 396, 1043-1058.

Stordeur C, Puth K, Saenz JP, Ernst R.
Crosstalk of lipid and protein homeostasis to maintain membrane function.

Biological Chemistry (2013) 395, 313-326.

Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese RF Jr, Simons K, Krogan NJ, Ernst R.
A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.
Molecular Cell (2013) 51, 519-530.

Ernst R, Claessen JH, Mueller B, Sanyal S, Spooner E, van der Veen AG, Kirak O, Schlieker CD, Weihofen WA, Ploegh HL.
Enzymatic blockade of the ubiquitin-proteasome pathway.
PLoS Biology (2011) 8(3):e1000605.
Featured as Editors' Choice in Science, Issue 1st of April 2011 "A less toxic treatment"

Ernst R, Kueppers P, Stindt J, Kuchler K, Schmitt L.
Multidrug efflux pumps: Substrate selection in ATP-binding cassette multidrug efflux pumps - first come, first served?
FEBS Journal (2010) 277, 540-549.

Ernst R, Mueller B, Ploegh HL, Schlieker C.
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.
Molecular Cell (2009) 36, 28-38.

Ernst R, Kueppers P, Klein CM, Schwarzmueller T, Kuchler K, Schmitt L.
A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5.
PNAS (2008) 105, 5069-5074.