Group Members

(For e-mail, just click on the name after "e-mail")

Dr. Klaas Martinus Pos
Professor & Group Leader     
phone +49-(0)69-798-29251
e-mail:

Beate Braungart     
Administrative assistant
phone +49-(0)69-798-29238
e-mail:

Senior Scientists

Dr. Denys Pogoryelov      
XtaLab Facility Leader
Phone +49-(0)69-798-29236
e-mail: 

Dr. Oliver Richter     
phone +49-(0)69-798-29240
e-mail: 

Postdocs

Dr. Viveka Malviya Nand
phone +49-(0)69-798-29242
e-mail:

Dr. Heng-Keat Tam
phone: +49-(0)69-798-29242
e-mail:

Graduate students

Jenifer Cuesta Bernal
phone +49-(0)69-798-29240
e-mail:

Selena Đorđević
+49-(0)69 - 798 29241
e-mail: 

Wuen Ee (Wendy) Foong
Phone: +49-(0)69-798-29242
Email: 

Emanuele Marine
phone +49-(0)69-798-29241
e-mail:

Reinke Müller
phone: +49-(0)69 - 798 29241
e-mail:

Alina Ornik     
phone +49-(0)69-798-29241
e-mail:

Anastasia Salisowski
phone +49-(0)69-798-29241
e-mail:

Nina Uhl
phone +49-(0)69-798-29242
e-mail:

Julia Wilhelm    
phone +49-(0)69-798-29241
e-mail:

Narek Yousefian
phone+49-(0)69-798-29241
e-mail: 

Technicians

Jasmin El-Delik       
phone +49-(0)69-798-29240
e-mail:

Christian Groß
phone: +49-(0)69-798-29236
e-mail:

Andrea Herrmann
phone +49-(0)69-798-29242
e-mail.

Publications 2017

Müller, R. T., Travers, T., Cha, H., Phillips, J., Gnanakaran, S., Pos, K. M.* (2017) Switch loop flexibility affects substrate transport of the AcrB efflux pump. Journal of Molecular Biology, in press.
PubMed

Gilardi A., Bhamidimarri S. P., Brönstrup M., Bilitewski U., Marreddy R. K. R., Pos K. M., Benier L., Gribbon P., Winterhalter M., Windshügel B. (2017) Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt. Biochim. Biophys. Acta. 1861: 2702-2709.
PubMed

Masi, M., Réfregiers, M, Pos K. M., Pagès, J-M. (2017) Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria. Nature Microbiol. 2: 17001.
PubMed

Schimo, S.#, Wittig, I.#, Pos, K. M.*, Ludwig, B.* (2017) Cytochrome c oxidase biogenesis and metallochaperone interactions: Steps in the assembly pathway of a bacterial complex. PLoS One 12: e0170037
PubMed

Nöll, A.#, Thomas, C.#, Herbring, V.#, Zollmann, T., Barth, K., Mehdipour, A. R., Tomasiak, T. M., Brüchert, S., Joseph, B., Abele, R., Oliéric, V., Wang, M., Diederichs, K., Hummer, G., Stroud, R. M., Pos, K. M., Tampé, R. (2017) Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP. Proc Natl Acad Sci U S A. 114: E438-E447.
PubMed

#equally contributed
*corresponding author

 

Publications 2016

Oswald, C.#, Tam, H-K.#, Pos, K. M.* (2016) Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB. Nat. Commun. 7: 13819
PubMed

Vargiu, A. V., Pos, K. M., Poole, K., Nikaido, H. (2016) Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria. Front Microbiol.7: 833
PubMed

Sjuts H., Vargiu A. V.*, Kwasny S. M., Nguyen S. T., Kim H-S., Ding X., Ornik A. R., Ruggerone P., Bowlin T., Nikaido H*., Pos K. M.*, Opperman T. J.* (2016) Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc. Nat. Acad. Sci. USA 113: 3509-3514
PubMed

Daury, L., Orange, F., Taveau, J-C., Verechere, A., Monlezun, L., Marreddy, R. K., Picard, M., Broutin, I., Pos, K. M., Lambert, O. (2016) Tripartite assembly of RND multidrug efflux pumps. Nat. Commun. 7: 10731
PubMed

Lytvynenko, I., Brill, S., Oswald, C., Pos, K. M.* (2016) Molecular basis of polyspecificity of the small multidrug resistance efflux pump AbeS from Acinetobacter baumannii J. Mol. Biol. 428: 644-657
PubMed

Hammerschmidt C., Klevenhaus Y., Koenigs A., Hallström T., Fingerle V., Skerka C., Pos K. M., Zipfel P. F., Wallich R., Kraiczy P. (2016) BGA66 and BGA71 facilitate complement resistance of Borrelia bavariensis by inhibiting assembly of the membrane attack complex. Mol Microbiol. 99: 407-424
PubMed

#equally contributed
*corresponding author