Institute of Biochemistry
Cellular Biochemistry - Prof. Dr. Tampé

Stefan E, Obexer R, Hofmann S, Vu Huu K, Huang Y, Morgner N, Suga H, Tampé R
De-novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition.
eLife 10 2021, e67732; doi:10.7554/eLife.67732

Sánchez MF, Els-Heindl S, Beck-Sickinger AG, Wieneke R, Tampé R
Photo-induced receptor confinement drives ligand-independent GPCR signaling.
Science.2021 Feb 25: eabb7657. doi: 10.1126/science.abb7657. Online ahead of print. PMID: 33632896

Stefan E, Hofmann S, Tampé R
A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter.
eLife 2020;9:e55943 doi: 10.7554

Sagert L, Hennig F, Thomas C, Tampé R
A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor.
eLife 2020;9:e55326 doi: 10.7554

Nürenberg-Goloub E, Kratzat H, Heinemann H, Heuer A, Kötter P, Berninghausen O, Becker T, Tampé R, Beckmann R
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
EMBO J.2020;e:103788 doi: 10.15252

Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A.
Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature. 2019 Jul 17. doi: 10.1038/s41586-019-1391-0. [Epub ahead of print]

Blees A, Januliene D, Hofmann T, Koller N, Schmidt C, Trowitzsch S, Moeller A, Tampé R.
Structure of the human MHC-I peptide-loading complex.
Nature. 2017 Nov 6. doi: 10.1038/nature24627.

Thomas C, Tampé R.
Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.
Science. 2017 Oct 12. pii: eaao6001. doi: 10.1126/science.aao6001.

Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Kötter P, Berninghausen O, Becker T, Beckmann R, Tampé R.
Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat Struct Mol Biol. 2017 May;24(5):453-460. doi: 10.1038/nsmb.3396. Epub 2017 Apr 3.

Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM*, Tampé R*, Craik CS*, Cheng Y*.
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.
Nature. 2015 Jan 15;517(7534):396-400. doi: 10.1038/nature13872. Epub 2014 Nov 2.

The most influential journals:

Impact Factor and Eigenfactor
Alan Fersht, Medical Research Council Centre for Protein Engineering, Cambridge,
United Kingdom
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www.eigenfactor.org

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