Institute of Biochemistry
Cellular Biochemistry - Prof. Dr. Tampé

Stefan E, Obexer R, Hofmann S, Vu Huu K, Huang Y, Morgner N, Suga H, Tampé R
De-novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition.
eLife 10 2021, e67732; doi:10.7554/eLife.67732

Sánchez MF, Els-Heindl S, Beck-Sickinger AG, Wieneke R, Tampé R
Photo-induced receptor confinement drives ligand-independent GPCR signaling.
Science.2021 Feb 25: eabb7657. doi: 10.1126/science.abb7657. Online ahead of print. PMID: 33632896

Stefan E, Hofmann S, Tampé R
A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter.
eLife 2020;9:e55943 doi: 10.7554

Sagert L, Hennig F, Thomas C, Tampé R
A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor.
eLife 2020;9:e55326 doi: 10.7554

Nürenberg-Goloub E, Kratzat H, Heinemann H, Heuer A, Kötter P, Berninghausen O, Becker T, Tampé R, Beckmann R
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
EMBO J.2020;e:103788 doi: 10.15252

Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A.
Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature. 2019 Jul 17. doi: 10.1038/s41586-019-1391-0. [Epub ahead of print]

Blees A, Januliene D, Hofmann T, Koller N, Schmidt C, Trowitzsch S, Moeller A, Tampé R.
Structure of the human MHC-I peptide-loading complex.
Nature. 2017 Nov 6. doi: 10.1038/nature24627.

Thomas C, Tampé R.
Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.
Science. 2017 Oct 12. pii: eaao6001. doi: 10.1126/science.aao6001.

Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Kötter P, Berninghausen O, Becker T, Beckmann R, Tampé R.
Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat Struct Mol Biol. 2017 May;24(5):453-460. doi: 10.1038/nsmb.3396. Epub 2017 Apr 3.

Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, Tomasiak TM, Brüchert S, Joseph B, Abele R, Oliéric V, Wang M, Diederichs K, Hummer G, Stroud RM, Pos KM, Tampé R.
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc Natl Acad Sci U S A. 2017 Jan 9. pii: 201620009. doi: 10.1073/pnas.1620009114. [Epub ahead of print]

Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM*, Tampé R*, Craik CS*, Cheng Y*.
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.
Nature. 2015 Jan 15;517(7534):396-400. doi: 10.1038/nature13872. Epub 2014 Nov 2.

The most influential journals:

Impact Factor and Eigenfactor
Alan Fersht, Medical Research Council Centre for Protein Engineering, Cambridge,
United Kingdom
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www.eigenfactor.org

More publications - Institute of Biochemistry

see research group:

Alexander Gottschalk