Institute of Biochemistry

Publications 2013

de Bono M, Schafer WR, Gottschalk A. (2013) Optogenetic actuation, inhibition, modulation and readout for neuronal networks generating behavior in the nematode Caenorhabditis elegans. In "Optogenetics"; Hegemann P, Sigrist S (editors), De Gruyter, Dahlem Workshop Reports

Kittelmann M, Liewald JF, Hegermann J, Schultheis C, Brauner M, Steuer Costa W, Wabnig S, Eimer S, and Gottschalk A.  (2013) In vivo synaptic recovery following optogenetic hyperstimulation. PNAS 110: E3007-E3016

Smith CJ, O’Brien T, Chatzigeorgiou M, Spencer WC, Feingold-Link E, Husson SJ, Hori S, Mitani S, Gottschalk A, Schafer WR, Miller DM. (2013) Sensory Neuron Fates Are Distinguished by a Transcriptional Switch that Regulates Dendrite Branch Stabilization. Neuron 79: 266–280

Husson SJ, Gottschalk A and Leifer AM. (2013) Optogenetic manipulation of neural activity in C. elegans: from synapse to circuits and behavior. Biol. Cell 105(6): 235-50

Akerboom, J, Carreras Calderon N, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ, Patel R, Pulver SR, Wardill TJ, Fischer E, Schüler C, Chen T-W, Sarkisyan, KS, Marvin JS, Bargmann, CI, Kim DK, Kügler S, Lagnado L, Hegemann P, Gottschalk A, Schreiter ER and Looger LL. (2013) Genetically encoded calcium indicators for multi-color neural activity imaging in combination with optogenetics. Front. Molec. Neurosci. 6: 2

Publications 2012

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A and Eimer S. (2012) RAB5 and RAB10 cooperate to regulate neuropeptide release in Caenorhabditis elegans. PNAS 109: 18944-9

Erbguth K, Prigge M, Schneider F, Hegemann P and Gottschalk A. (2012)           Bimodal activation of different neuron classes with the spectrally red-shifted Channelrhodopsin chimera C1V1 in Caenorhabditis elegansPLoS ONE 7: e46827

Schmitt C, Schultheis C, Pokala N, Husson SJ, Liewald JF, Bargmann, CI and Gottschalk A. (2012) Specific expression of Channelrhodopsin-2 in single neurons of Caenorhabditis elegans. PLoS ONE 7: e43164

Brieke C, Rohrbach F, Gottschalk A, Mayer G and Heckel A. (2012)
Light controlled tools. Angew. Chem. Int. Ed. 51: 8446-8476

Husson S, Steuer Costa W, Schmitt C and Gottschalk A. (2012)
Keeping track of worm trackers.

Husson SJ, Liewald JF, Schultheis C, Stirman JN, Lu H and Gottschalk A. (2012)     Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans. PLoS ONE 7: e40937

Husson S, Steuer Costa W, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller III DM, Lu H and Gottschalk A. (2012)
Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.
Curr. Biol. 22: 743-752.

Stirman J, Crane M, Husson S, Gottschalk A and Lu H. (2012) 
A multispectral optical illumination system with precise spatiotemporal control for the manipulation of optogenetic reagents
Nat. Prot. 7: 207-220.

Publications 2011

Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura J. (2011)
C. elegans selects distinct crawling and swimming gaits via dopamine and serotonin

PNAS 108: 17504-17509.

Schultheis C, Brauner M, Liewald JF, Gottschalk A.
Optogenetic analysis of GABAB receptor signalling in Caenorhabditis elegans motor neurons.
J. Neurophysiol. 106: 817-827. Epub 2011 May 25.

Schultheis C, Liewald JF, Bamberg, E, Nagel G, Gottschalk A.
Optogenetic long-term manipulation of behavior and animal development.
PLoS One 6(4): e18766.

Stirman J, Crane M, Husson S, Wabnig S, Schultheis C, Gottschalk A*, Lu H*.  (*corresponding authors)
Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans.
Nat. Methods. 8:153-8. Epub 2011 Jan 16.

Weissenberger S, Schultheis C, Liewald J, Erbguth K, Nagel G, Gottschalk A.
PACα - an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans.
J. Neurochem. 116(4):616-25. doi: 10.1111/j.1471-4159.2010.07148.x. Epub 2011 Jan 20.

Publications 2010

Stirman J, Brauner M, Gottschalk A, Lu H.
High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics.
J. Neurosci Meth. 191(1):90-3. Epub 2010 Jun 9.