Structural Biology of Membrane-Associated Photosynthetic Proteins
Unraveling the Molecular Mechanisms of Complex Membrane-Associated Photosynthetic Proteins

The growing global demand for energy presents a critical challenge, as most conventional energy sources are either finite, harmful to the environment, or major contributors to greenhouse gas emissions. Solar energy offers a clean and sustainable alternative, but current technologies for converting sunlight into transportable fuels remain inefficient and costly. Remarkably, nature has already solved this problem through photosynthesis—a process by which plants, cyanobacteria, and algae efficiently capture and utilize solar energy.

Our research aims to unravel the intricate molecular mechanisms behind photosynthesis. Using advanced spectroscopic techniques and cutting-edge structural analysis methods, we strive to decode these natural processes at the atomic level. This foundational knowledge not only deepens our understanding of biological energy conversion but also provides a blueprint for developing artificial photosynthesis technologies, paving the way for sustainable energy solutions.

Our lab specializes in exploring the structural and functional mechanisms of complex membrane proteins central to photosynthesis. At the heart of our research is Photosystem II (PSII)—a key model system for studying membrane protein complexes and their role in life-sustaining processes. By utilizing state-of-the-art tools such as X-ray free electron laser (XFEL) crystallography, cryo-electron microscopy (cryo-EM), and a range of spectroscopic techniques, we capture dynamic biological processes at near-atomic resolution. Through collaborative efforts with leading national and international research groups, we address significant challenges in structural biology and photosynthesis research.

Stefan Frühschulz
PhD student
Institute of Biochemistry,
Biocenter N220 | room 1.03
Goethe-University Frankfurt
Max-von-Laue-Str. 9
D-60438 Frankfurt/M., Germany
Phone: +49-(0)-69 - 798 29261
Email:
fruehschulz(at)biochem.uni-frankfurt.de