Membrane Transport Machineries - Prof. Dr. Pos
Nöll, A.#, Thomas, C.#, Herbring, V.#, Zollmann, T., Barth, K., Mehdipour, A. R., Tomasiak, T. M., Brüchert, S., Joseph, B., Abele, R., Oliéric, V., Wang, M., Diederichs, K., Hummer, G., Stroud, R. M., Pos, K. M., Tampé, R. (2017)
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc Natl Acad Sci U S A. 114: E438-E447.
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Oswald, C.#, Tam, H-K.#, Pos, K. M.* (2016)
Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB.
Nat. Commun. 7: 13819
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Daury, L., Orange, F., Taveau, J-C., Verechere, A., Monlezun, L., Marreddy, R. K., Picard, M., Broutin, I., Pos, K. M., Lambert, O. (2016)
Tripartite assembly of RND multidrug efflux pumps.
Nat. Commun. 7: 10731
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Sjuts H., Vargiu A. V.*, Kwasny S. M., Nguyen S. T., Kim H-S., Ding X., Ornik A. R., Ruggerone P., Bowlin T., Nikaido H*., Pos K. M.*, Opperman T. J.* (2016)
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Proc. Nat. Acad. Sci. USA 113: 3509-3514
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Eicher, T., Seeger, M. A.., Anselmi, C., Zhou, W., Brandstätter, L., Verrey, F., Diederichs, K., Faraldo-Gómez, J. D.*, Pos, K. M.* (2014)
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.
eLife, 3: e03145
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Eicher, T., Cha, H., Seeger, M.A., Brandstätter, L., Bohnert, J.A., Kern, W.V., Verrey, F., Grütter, M. G., Diederichs, K., Pos, K. M.* (2012)
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc. Nat. Acad. Sci USA, 109: 5687-5692
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The most influential journals:
Impact Factor and Eigenfactor
Alan Fersht, Medical Research Council Centre for Protein Engineering, Cambridge,
United Kingdom
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www.eigenfactor.org
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