Institute of Biochemistry

Publications 2026

Bulankina AV, Richter RM, Nettler JH, Yamane D, Grimm C, Karami Y, Stanton RA, Introini V, Hermann J, Charif H, König MS, Stroß C, Ortiz C, Kraus N, Wood D, Abele R, Maigret B, Schinazi RF, Zeuzem S, Biondi RM, Yi M, Tampé R, Kudryashev M, Welsch C
Phospholipid-driven conformational switching of 1 HCV NS5A links protein folding to replication membrane remodeling.
Science Advances, in press (2026)
 

Schäffner M, Smith CA, Tampé R, Grubmüller H 
Braess paradox in enzyme kinetics: Asymmetry from population balance without direct cooperativity.
J Chem Theory Comput, in press (2026)
doi:10.1021/acs.jctc.5c01269

Publications 2025

Stolz M, Susac L, Fahim A, Keller R, Saggau L, Mancia F, Trowitzsch S, Tampé R
US6 hijacks the peptide-loading complex by trapping transport-chaperone dynamics.
Science Adv, accepted, BioRxiv 661491 (2025)
doi:10.1101/2025.06.25.661491

Heinke TJ, Fahim A, Popovic N, Rath T, Morgner N, Trowitzsch S, Tampé R
Reconstitution of glycan-driven MHC I recycling reveals calreticulin as mediator between TAPBPR and tapasin.
BioRxiv 2025.11.25.690393 (2025)
doi:10.1101/2025.11.25.690393

Nocker C, Pecak M, Nocker T, Fahim A, Susac L, Tampé R
Single-molecule dynamics reveal ATP binding alone powers substrate translocation by an ABC transporter.
Nat Commun , accepted, BioRxiv 690960 (2025)
doi:10.1101/2025.11.27.690960

Schäffner M, Smith CA, Tampé R, Grubmüller H
Braess' paradox in enzyme kinetics: asymmetry from population balance without direct cooperativity.
BioRxiv, 2025.07.30.667590 (2025)
doi:10.1101/2025.07.30.667590
 

Cebrian I, Dinamarca S, Pena Rodriguez MJ, Priego E, Brouwers N, Barends M, Brunnberg J, Tampé R, Blanchard N, Sancho D, Malhotra V
Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules.
Cell Rep, 44, 115333 (2025)
doi:10.1016/j.celrep.2025.115333