Publications 2020

Thomas C, Tampé R.
Structural and mechanistic principles of ABC transporters
Annu Rev Biochem 89, 605-36. doi:10.1146/annurev-biochem-011520-105201

Stefan E, Hofmann S, Tampé R.
A single power troke by ATP binding drives substrate translocation in a heterodimeric ABC transporter
eLife 9, e55943. doi:10.7554/eLife.55943

De Waard AA, Verkerk T, Jongsma MLM, Hoefakker K, Sethumadhavan S, Gerke C, Bliss S, Kong X, Janssen GMC, de Ru AH, Class FHJ, Mulder A, Tampé R, van Veelen PA, Halenius A, Spaapen RM.
PACK: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
Eur J Immunol 51, 734-737. doi:10.1002/eji.202048599

Thomas C, Aller SG, Beis K, Carpenter EP, Chang G, Chen L, Dassa E, Dean M, Doung van Hoa F, Ekiert D, Ford R, Gaudet R, Gong X, Holland IB, Huang Y, Kahne DK, Kato H, Kornakis V, Koth CM, Lee Y, Lewinson O, Lill R, Martinoia E, Marakami S, Pinkett HW, Poolman B, Rosenbaum D, Sarkadi B, Schmitt L, Schneider E, Shi Y, Shyng SL, Slotboom DJ, Tajikhorshid E, Tieleman DP, Ueda K, Váradi A, Wen PC, Yan N, Zhang P, Zheng H, Zimmer J, Tampé R.
Structural and functional diversity calls for a new classification of ABC transporters
FEBS Lett 594, 2767-75. doi:10.1002/1873-3468-13936

Barth K, Rudolph M, Diederichs T, Prisner TF, Tampé R, Joseph B.
Thermodynamic basis for conformational coupling in an ATP-binding cassette exporter
J Phys Chem Lett 11, 7946-53. doi:10.1021/acs.jpclett.0c01876

Liamas E, Black RA, Mulheran PA, Tampé R, Wieneke R, Thoams ORT, Zhang ZJ.
Probing fibronectin adsorption on chemically defined surfaces by means of single molecule force microscopy
Sci Rep 10, 15662. doi:10.1038/s41598-020-72617-z

Dultz G, Shimakami T, Schneider M, Murai K, Yamane D, Marion A, Zeitler TM, Stross C, Grimm C, Richter RM, Bäumer K, Yi M, Biondi RM, Zeuzem S, Tampé R, Antes I, Lange CM, Welsch C.
Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors
J Biol Chem 295, 13862-74. doi:10.1074/jbc.RA120.013898

Mavridis G, Arya R, Domnick A, Zoidakis J, Makridakis M, Vlahou A, Mpakali A, Lelis A, Georgiadis D, Tampé R, Papakyriakou A, Stern L, Stratikos E.
A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by ER aminopeptidase 1
J Biol Chem 295, 7193-210. doi:10.1074/jbc.RA120.012976
Front Cover Story in J Biol Chem 295, May 22, 2020
Editor's pick: Colbert JD & Rock KL (2020) J Biol Chem.

Khoo KK, Galleano I, Gasparri F, Wieneke R, Harms H, Poulsen MH, Chua HC, Wulf M, Tampé R, Pless SA.
Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing
Nat Commun 11, 2284. doi:10.1038/s41467-020-16308-6

Sagert L, Hennig F, Thomas C, Tampé R.
A loop structure allow TAPBPR to exert its dual function as MHC I chaperon and peptide editor
eLife 9, e55326. doi:10.7554/eLife.55326

Brüchert S, Joest EF, Gatterdam K, Tampé R.
Ultrafast in-gel detection by fluorescent upper-chelator probes with HisQuick-PAGE
Commun Biol 3, 138. doi:10.1038/s42003-020-0852-1

Nürenberg-Goloub E, Kratzat H, Heinemann H, Heuer A, Kötter P, Berninghause O, Becker T, Tampé R, Beckmann R.
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex
EMBO J 39, e103788. doi:10.15252/embj.2019103788

Trowitzsch S, Tampé R.
Multifunctional chaperone and quality control complexes in adaptive immunity
Annu Rev Biophys 49, 135-161. doi:10.1146/annurev-biophys-121219-081643

Publications 2019

Nürenberg-Goloub E, Tampé R.
Ribosome recycling in mRNA translation, quality control, and homeostasis
Biol Chem, 401, 47-61. doi:10.1515/hsz-2019-0279

Diederichs T, Pugh G, Dovey A, Xing Y, Burns JR, Nguyen QH, Tornow M, Tampé R, Howorka S.
Synthetic protein-conductive membrane nanopores built with DNA
Nat Commun 10, 5018. doi:10.1038/s41467-019-12639-y

Bock C, Zollmann T, Lindt KA, Tampé R, Abele R.
Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy
Sci Rep 9, 1184. doi:10.1038/s41598-019-48343-6

Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A.
Conformation space of a heterodimeric ABC exporter under turnover conditions
Nature 471, 580-3. doi:10.1038/s41586-019-1391-0
Front Cover Story in Nature 471

Gouridis G, Hetzert B, Kiosze-Becker K, de Boer M, Heinemann H, Nürenberg-Goloub E, Cordes T, Tampé R
ABCE1 controls ribosome recycling by an asymmetric dynamic conformation equilibrium
Cell Rep 28, 723-634. doi:10.1016/j.celrep.2019.06.052

Döring M, Blees H, Koller N, Tischer-Zimmermann S, Müsken M, Henrich F, Becker J, Garbski E, Wang J, Jannssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampé R, Kalinke U.
Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation
Blood Adv 3, 839-50. doi:10.1182/bloodadvances.2018027268

Baldering TN, Dietz MS, Gatterdam K, Karathanasis C, Wieneke R, Tampé R, Heilemann M.
Synthetic and genetic dimers as quantification ruler for single-molecule counting with PALM
Mol Biol Cell, mbcE18100661. doi:10.1091/mbc.E18-10-0661

Thomas C, Tampé R.
MHC I chaperone complexes shaping immunity
Curr Opin Immunol 58, 9-15. doi:10.1016/j.coi.2019.01.001

Graab R, Brock C, Weiss K, Hirth A, Koller N, Braner M, Jung J, Loehr F, Tampé R, Behrends C, Abele R.
Lysosomal targeting of the ABC transporter TAPL is determined by membrane localized charged residues
J Biol Chem 294, 7308-23. doi:10.1074/jbc.RA118.007071

Wieneke R, Tampé R.
Multivalent chelators for in vivo protein labeling
Angew Chem Int Ed 58, 8278-90. doi:10.1002/anie.201811293