Publications
Publications 2024
Wilhelm, J., Pos, K. M.* (2024) Molecular insights into the determinants of substrate specificity and efflux inhibition of the RND efflux pumps AcrB and AdeB Microbiology (Reading), 170: 001438 Pubmed
Vieira Da Cruz, A., Jiménez-Castellanos, J. C., Börnsen, C., Van Maele, L., Compagne, N., Pradel, E., Müller, R. T., Meurillon, V., Soulard, D., Piveteau, C., Biela, A., Dumont, J., Leroux, F., Deprez, B., Willand, N., Pos, K. M*., Frangakis, A. S.*, Hartkoorn, R. C.*, Flipo, M.* (2024) Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae EMBO Mol Med, 16: 93-111 Pubmed
Pos, K. M.* (2024) RND multidrug efflux transporters: similar appearances, diverse actions J Bacteriol, 206: e0040323 Pubmed
Publications 2023
Irianti, I. M., Vincken, J. P., van Dinteren, S., Ter Beest, E., Pos, K. M.*, Araya-Cloutier, C.* (2023) Prenylated isoflavonoids from Fabaceae against the NorA efflux pump in Staphylococcus aureus. Sci Rep 13: 22548 Pubmed
Roden, A., Engelin, M. K., Pos, K. M., Geertsma, E. R.* (2023) Membrane-anchored substrate binding proteins are deployed in secondary TAXI transporters Biol Chem 404: 715-725 Pubmed
Compagne, N., Vieira Da Cruz, A., Müller, R. T., Hartkoorn, R. C., Flipo, M., Pos, K. M.* (2023) Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria. Antibiotics (Basel) 12: 180 Pubmed
Publications 2022
Tam, H. K.*, König, P., Himpich, S., Ngu, N. D., Abele, R., Müller, V., Pos, K. M. (2022) Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix-loop-helix-mediated dimer formation Proc Natl Acad Sci U S A. 119: e2107994119 Pubmed
Plé, C., Tam, H. K., Vieira Da Cruz, A., Compagne, N., Jiménez-Castellanos, J. C., Müller, R. T., Pradel, E., Foong, W. E., Malloci, G., Ballée, A., Kirchner, M. A., Moshfegh, P., Herledan, A., Herrmann, A., Deprez, B., Willand, N., Vargiu, A. V., Pos, K. M.*, Flipo, M.*, Hartkoorn, R. C.* (2022) Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps Nat Commun 13: 115 Pubmed
Group Members
(For e-mail, just click on the name after "Email")
Dr. Klaas Martinus Pos
Professor & Group Leader
phone +49-(0)69-798-29251
Email: pos
Ute Imkampe
Administrative assistant
phone +49-(0)69-798-29238
Email: imkampe
Graduate students
Eszter Lodinsky
phone +49-(0)69-798 29242
Email: lodinsky
Pei-Yu Yu
phone +49-(0)69-798 29241
Email: yu
Liliana Fernandes da Costa
phone +49-(0)69-798 29240
Email: da costa
Luise Stadler
phone +49-(0)69-798 29240
Email: stadler
Daitian Xu
phone +49-(0)69-798 29241
Email: xu
Max Borgosch
phone +49-(0)69-798 29242
Email: borgosch
Technicians
Jasmin El-Delik
phone +49-(0)69-798-29240
Email: el-delik
Christian Groß
phone: +49-(0)69-798-29236
Email: groß